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所在位置:所有产品 > 抗体抗原 > 一抗 > TP53BP1抗体
TP53BP1抗体图片
产品货号:
Z28560
中文名称:
TP53BP1抗体
英文名称:
Anti-TP53BP1 Antibody
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称Anti-TP53BP1 Antibody
指标别名TP53BP1;TP53-binding protein 1;53BP1;p53-binding protein 1;p53BP1
克隆性Polyclonal
检验物种human,mouse,rat
应用范围WB,IHC,ICC
基因名称TP53BP1
抗体来源Rabbit
抗体类型IgG
免疫原A synthetic peptide corresponding to a sequence at the C-terminus of human 53BP1(1955-1972aa ERIGFKQHPKYKHDYVSH),identical to the related mouse sequence.
实际分子量450KD
成分500μg/mL antibody with PBS,0.02% NaN3,1mg BSA and 50% glycerol.
纯化方式Immunogen affinity purified.
浓度500μg/mL
产品形态溶液
保存条件12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing.
背景资料TP53BP1(Tumor Protein p53-Binding Protein 1),also called 53BP1,is a protein that in humans is encoded by the TP53BP1 gene.Iwabuchi et al.(1998) mapped the TP53BP1 gene to 15q15-q21 by FISH.Iwabuchi et al.(1994) showed that TP53BP1 binds to the conformationally sensitive central domain of wildtype p53 but not to mutant p53 in vitro.Immunoblot analysis by Iwabuchi et al.(1998) showed that expression of TP53BP1 or TP53BP2 enhances the transactivation function of p53 and induces the expression of p21(CDKN1A).Wang et al.(2002) used small interfering RNA directed against TP53BP1 in mammalian cells to demonstrate that TP53BP1 is a key transducer of the DNA damage checkpoint signal.TP53BP1 was required for p53 accumulation,G2/M checkpoint arrest,and the intra-S-phase checkpoint in response to ionizing radiation.
Uniprot IDQ12888
推荐配套试剂Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。
基因名全称tumor protein p53 binding protein 1
蛋白名全称Tumor suppressor p53-binding protein 1
推荐稀释比
Western blot (WB) 1:500~2000
Immunohistochemistry in paraffin section (IHC) 1:50~400
Immunocytochemistry 1:50~400
(Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user.

相关搜索:TP53BP1抗体TP53BP1多抗Anti-TP53BP1 Antibody
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